FAQ

Understanding Cannabinoids & the Endocannabinoid System
The Endocannabinoid System (ECS) is a complex, body-wide signaling network that helps regulate things like mood, sleep, pain, inflammation, memory, and even hormone balance. It acts like a master balancer, helping your body return to homeostasis when things feel "off." During perimenopause and menopause, natural estrogen declines - and because estrogen helps stimulate ECS activity, this can throw off the balance of your entire system. That’s one reason so many women experience symptoms like insomnia, brain fog, joint pain, and anxiety during this time. Supporting the ECS with cannabinoids can help restore equilibrium where your body needs it most.¹
These are all cannabinoids - compounds naturally found in the hemp plant that interact with your ECS. Each has unique properties:
- CBD (Cannabidiol): Anti-inflammatory and calming. Helps ease anxiety, reduce pain, and support restful sleep.
- CBG (Cannabigerol): Known as the “mother of all cannabinoids,” it’s especially helpful for focus and cognitive clarity - making it a powerful ally against hormonal brain fog.
- CBN (Cannabinol): Often called the “sleep cannabinoid.” It supports deep relaxation and can extend sleep cycles.
THC (Tetrahydrocannabinol): In small amounts, THC enhances the effects of other cannabinoids without causing intoxication. It can help deepen sleep, reduce pain perception, and support emotional balance.
CLEA combines these cannabinoids intentionally, in ratios designed to address specific midlife symptoms like sleeplessness, inflammation, mental fog, and anxiety.
So many products are either under-dosed, over-processed, or not formulated with midlife women in mind. CLEA is different. We formulate specifically for the menopause journey, targeting the symptoms that most commonly affect women in perimenopause and beyond. Our products use clean, full-spectrum hemp extracts, never isolates or synthetics. We also make sure you’re getting meaningful doses - no fluff or filler. And we never use preservatives, chemical solvents, or artificial anything. Just pure, plant-powered support, third-party tested for safety and potency.
Symptom Relief & Usage
Yes - and that’s exactly why we created CLEA. These symptoms are among the most common and frustrating for women in midlife, and research increasingly supports the role of cannabinoids in easing them:
- Sleep: CBD, CBN, and low-dose THC together can help women fall asleep faster, stay asleep longer, and wake up feeling more rested.²
- Brain fog: CBG has shown promise in promoting mental clarity, neuroprotection, and motivation.³
- Anxiety: CBD interacts with serotonin receptors to support emotional regulation and calm.⁴
- Joint pain & inflammation: Cannabinoids can reduce inflammatory markers and help manage pain without harsh side effects.⁵
CLEA’s formulas are built to support these needs - because we’ve lived them, too.
No. Our formulas are designed for function, not intoxication. Even our SLEEP capsules, which contain a microdose of THC, are crafted to relax, not impair. At 2mg, the THC works synergistically with CBD and CBN to support sleep without producing a high. You can feel safe, in control, and grounded when using our products.
Every body is different, and consistency is key. Some women feel a difference with SLEEP almost immediately. For others, especially with CBD-based support like EASE, it may take 2-4 weeks for your system to fully absorb the benefits. We recommend taking CLEA products routinely, at the same time each day, to help your body respond consistently. This is not a quick fix - it’s a conversation between you and your body.
Our Clean Formulation Promise
It means that what you put in - and on - your body matters deeply to us. Every CLEA product is made with organic, full-spectrum hemp, grown and harvested without chemical fertilizers or pesticides. We never use preservatives, synthetic additives, or harsh solvents in our extraction process. Our ingredients are intentionally chosen, ethically sourced, and rigorously tested. We’re also committed to no animal testing - ever. From the soil to the supplement, we believe you deserve clean, safe, potent support you can trust.
Nope. None. CLEA products are preservative-free, fragrance-free, and filler-free. That means no gums, dyes, parabens, or synthetic stabilizers. Just plant-based, purpose-driven ingredients formulated for your midlife body.
Yes. Every single batch of CLEA products is third-party tested for cannabinoid content, heavy metals, residual solvents, microbial contaminants, and more. You deserve transparency - and we’re proud to provide it. If you'd like to see our lab results, just ask. We’ll never hide what’s inside.
Yes. All CLEA products are 100% vegan and cruelty-free. We never test on animals, and none of our ingredients come from animal sources. Supporting your wellbeing shouldn’t come at the cost of another life.
Legal & Safety Questions
CLEA products are 100% legal under federal U.S. law. The 2018 Farm Bill made it legal to grow, sell, and use hemp-derived cannabinoid products - so long as they contain less than 0.3% THC by dry weight. All CLEA formulations meet this threshold. We use hemp grown in compliance with these guidelines and test rigorously to ensure you’re always getting legal, safe, high-quality support.
Possibly - especially with our SLEEP capsules, which contain small amounts of THC. While unlikely at our low doses, trace THC can accumulate in the body over time and show up on sensitive tests. If drug testing is a concern, we recommend speaking with your employer or healthcare provider before starting any cannabinoid product.
In most cases, yes. Many of our customers find that combining HRT with CLEA’s plant-based products gives them even more support - because they work in different ways. HRT helps replace declining sex hormones like estrogen, progesterone, and testosterone, while cannabinoids interact with your endocannabinoid system to restore balance in mood, inflammation, sleep, and more. As always, we recommend checking with your provider - especially if you’re using prescription medications.
Product-Specific Support
Here’s a quick cheat sheet to guide you:
- EASE (CBD): Supports anxiety, body tension, inflammation, and mood regulation
- FOCUS (CBG): Targets mental clarity, memory, and brain fog
- SLEEP (CBD, CBN, THC): Designed for deep, uninterrupted sleep and nervous system restoration
- NOURISH Body Oil (CBD): Soothes sore muscles, calms inflamed skin, and deeply hydrates
Still unsure? Try our CLEA Quiz to find your personalized support path.
- EASE: Evening or before bed - it can help support emotional balance, ease inflammation, and deepen the effects of the SLEEP capsules
- FOCUS: Morning or early afternoon - great for alertness and mental clarity
- SLEEP: 30–60 minutes before bed - ideally on a consistent schedule for best results
NOURISH: Anytime - after showering, before bed, post-workout, or whenever your body needs a moment of care
Citations for CLEA Midlife FAQ
– Bradshaw, H. B., et al. (2013). Sex steroid hormone modulation of the endocannabinoid system. Current Opinion in Pharmacology, 13(4), 562-568.
https://doi.org/10.1016/j.coph.2013.05.007
– Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, cannabinoids, and sleep: A review of the literature. Current Psychiatry Reports, 19(4), 23.
https://doi.org/10.1007/s11920-017-0775-9
– Borrelli, F., et al. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306-1316.
(Note: While focused on inflammation, the study identifies neuroprotective potential of CBG.)
https://doi.org/10.1016/j.bcp.2013.01.017
– Blessing, E. M., et al. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825-836.
https://doi.org/10.1007/s13311-015-0387-1
– Nagarkatti, P., et al. (2009). Cannabinoids as novel anti-inflammatory drugs. Future Medicinal Chemistry, 1(7), 1333–1349.
https://doi.org/10.4155/fmc.09.93